The Research
What the science says about psychedelic medicine, paired with the people on our show who have lived it. This is a curated library, not a news feed. We keep it short on purpose.
Last reviewed: November 2, 2026 · Next review: February 2027
How we choose what's here
- Peer reviewed research or a registered clinical trial. Press releases alone don't count.
- Studies in people, unless an earlier study is truly foundational.
- Connected to a medicine we explore on the show.
- Big enough to change the conversation: a landmark result, a regulatory milestone, or a major replication.
Each substance page holds a few foundational studies and no more than five current items. When something new comes in, the oldest current item moves to the archive.
Strength of evidence
By medicine
Psilocybin
Depression, end of life distress, addiction.
DMT and Ayahuasca
Pairs with The DMT Chronicles.
5-MeO-DMT
Fast acting, early clinical work.
Ibogaine
Addiction and brain injury research.
MDMA
PTSD research and the FDA story.
Ketamine
The one already prescribed today.
By condition
Each condition links into the medicine pages, so nothing is written twice.
This page is for education only and is not medical advice. Most of these substances remain illegal under federal law and in most states. Talk with a qualified professional before making any health decision.