Ibogaine
A plant medicine from the root bark of the iboga shrub, used for generations in Bwiti ceremonies in Gabon. People report that a single treatment can sharply ease opioid withdrawal and cravings. It also carries real heart risks, which is why the research is moving carefully.
Last reviewed: November 2, 2026
The basics
Ibogaine produces a long, intense experience that can last a day or more, often with vivid reviews of one's life. Researchers are most interested in two uses: interrupting opioid and other addictions, and healing the effects of traumatic brain injury. Its biggest danger is to the heart. It can disturb the heart's rhythm, and deaths have been reported, mostly in settings without medical monitoring. Modern trials use heart monitoring throughout, and some add magnesium to protect the heart.
| Where | Status |
|---|---|
| United States, federal | Schedule I. The FDA has invited the first U.S. trial proposals. |
| Texas, Arizona and Mississippi | Funding state research programs. These fund studies, not public access. |
| Colorado | Personal use by adults 21 and over is decriminalized. No licensed centers offer it yet. |
| Outside the U.S. | Clinics in Mexico and some other countries offer it, outside U.S. oversight. |
Foundational studies
What's happening now
Capped at five. Oldest rotates to the archive at each review.
From the show
An ibogaine conversation
Coming soon.
Two Psychonauts, No Filter | DMT, 5-MeO-DMT, Ketamine & Beyond
Two experienced psychonauts, decades of exploration, and one candid conversation. Dr. DREAM and Tom share their personal journeys with 5-MeO-DMT, N,N-DMT, ketamine, ibogaine, psilocybin, salvia and more.
Watch on YouTube →Go deeper
This page is for education only and is not medical advice. Ibogaine is a Schedule I substance under federal law and can cause dangerous, sometimes fatal, heart rhythm problems. It should never be taken without medical screening and heart monitoring. Talk with a qualified professional before making any health decision.